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Spyre Therapeutics, Inc. short interest in 2025

In 2025, Spyre Therapeutics, Inc.'s disclosed short interest ran from 19.45% of shares outstanding on 15 Jan 2025 to 15.00% on 31 Dec 2025, a change of -4.45 percentage points. The year's high was 24.41% on 30 Apr 2025 and its low 14.38% on 28 Nov 2025, averaging 20.28% across 24 twice-monthly settlement dates. FINRA's days-to-cover figure peaked at 33.21 days on 30 May 2025. Full history: Spyre Therapeutics, Inc..

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By year: 2019 · 2020 · 2021 · 2022 · 2023 · 2024 · 2025 · 2026

Aggregate net short position time series for Spyre Therapeutics, Inc. in 2025

2025 in figures

Start of year
19.45% (15 Jan 2025)
End of year
15.00% (31 Dec 2025)
Change
-4.45 pp
High
24.41% (30 Apr 2025)
Low
14.38% (28 Nov 2025)
Average
20.28%
Highest days to cover
33.21 (30 May 2025)
SEC filings marked
10

Every report in 2025

Spyre Therapeutics, Inc. short interest in 2025
SettlementShort interestDays to coverFilings since previous
15 Jan 202519.45%18.05results (8-K)
31 Jan 202519.90%16.75
14 Feb 202519.30%17.06
28 Feb 202519.49%16.0810-K filed, results (8-K)
14 Mar 202520.94%16.08
31 Mar 202522.09%17.61
15 Apr 202522.85%11.52
30 Apr 202524.41%21.38
15 May 202520.37%20.7510-Q filed, results (8-K)
30 May 202520.03%33.21
13 Jun 202520.86%27.28
30 Jun 202522.35%16.95
15 Jul 202522.54%23.13
31 Jul 202521.32%23.35
15 Aug 202521.83%30.5010-Q filed, results (8-K)
29 Aug 202523.32%29.35
15 Sep 202522.82%28.53
30 Sep 202523.94%18.19
15 Oct 202522.17%9.19results (8-K)
31 Oct 202515.99%11.89
14 Nov 202516.06%20.1510-Q filed, results (8-K)
28 Nov 202514.38%18.26
15 Dec 202515.23%13.87
31 Dec 202515.00%14.06

See also: Spyre Therapeutics, Inc.'s full history · most shorted US stocks of 2025 · today's US league.

About this data

US short interest data: FINRA (finra.org), shown as reported shares short divided by SEC-reported shares outstanding for each settlement date. FINRA® is a registered trademark of the Financial Industry Regulatory Authority, Inc. This site is not affiliated with or endorsed by FINRA or the SEC; displayed for personal reference, bulk redistribution is not permitted (see terms). Nothing here is investment advice. Method: methodology.